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Pneumococcal Cell Wall Polysaccharide (CWPS)
Pneumococci produce a conserved sugar group antigen (CWPS, C‑Ps, teichoic acid). Research studies have shown at least two different variants, based on the quantity of phosphorylcholine (CWPS1 and CWPS2).
The product shown on this page, CWPS, contains solely CWPS1. For a product containing both CWPS1 and CWPS2, please refer to CWPS Multi.
Product description
Pneumococcal CWPS antigens (1 and 2) are produced by purification of CWPS from native pneumococci strains.
Clinical relevance
Streptococcus pneumoniae expresses a number of different sugars on the cell surface. Most sugars are in the cell capsule, which defines the pneumococcal serotypes currently known. In addition to the type‑specific capsule sugars, all pneumococci also express a group antigen, referred to as the cell wall polysaccharide (CWPS). CWPS is found in two different forms, depending on the quantity of phosphorylcholine per sugar unit. The capsule sugars are found in existing pneumococcal vaccines, partly in conjugate vaccine for children, but also in pure sugar vaccines for adults. They generate antibodies, which however do not protect against infection.
How to use
Pneumococcal CWPS is used as adsorption material in immunological investigations such as ELISA antibody assays, to evaluate serotype specific antibody levels in samples. The product needs to be used in accordance with the respective WHO training manual (1).
Product
| Article number | Product | Packing |
|---|---|---|
| 3459 | CWPS | 10 mg |
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Reference
- Training manual for Enzyme linked immunosorbent assay for the quantitation of Streptococcus pneumoniae serotype specific IgG (Pn PS ELISA).,accessed 14/11/2025